Promifen

Description

Description

Bodybuilders use Clomid to induce and induce endogenous testosterone production in the testicles Clomiphene avoid hormonal imbalances. Athletes show that a daily dose of 50-100mg of Clomid helps restore normal testosterone levels within 2 weeks.

Pharmacological effects

Pharmacology: Drugs – Anti-estrogens. It binds to estrogen receptors in the hypothalamus and ovaries. When ingested is well absorbed from the gastrointestinal tract. It is metabolized in the liver. Excreted in Galle, it undergoes enterohepatic recycling. Excreted from the body in the stool. T_1 / 2 5-7 days. At low doses, it increases the secretion of gonadotropins (prolactin, LH and FSH) and stimulates ovulation. When low levels of endogenous estrogen in the body have a mild estrogenic effect at high levels – anti-estrogenic. By reducing circulating estrogen levels, it promotes the secretion of gonadotropins. In large doses, slows down the secretion of gonadotropins. Gestagenic and androgenic activity no.

Indications

Application: anovulatory infertility (ovulation induction), dysfunctional uterine hemorrhage, amenorrhea (secondary disgonadotropnaya, postkontratseptivnaya form), galactorrhea (in relation to pituitary tumors), polycystic ovaries (Stein–Leventhal syndrome)–Frommelya and androgen deficiency, for the diagnosis of pituitary gonadotrophic function.

Contraindications

Hypersensitivity, severe renal insufficiency, uterine bleeding of unknown etiology, ovarian cyst, tumoral or pituitary insufficiency, pregnancy (including suspicion).

Side effects

Side effects: from the nervous system and sensory organs: headache, dizziness, depression, fatigue, anxiety, insomnia, blurred vision.

From the digestive tract: Nausea Vomiting.

Promifen