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Indeed, the agonist and antagonist activity ratio is 45/55. Tamoxifen is a chemically derived form of triphenylethylene. The drug belongs to the group of sex hormones. Originally it was used to treat cancer in women (breast cancer). Of course today Tamoxifen are much more common in sports and especially bodybuilding.

It's no secret that the majority of steroids undergo a taste which is converted into female sex hormones – estrogen. This can lead to a variety of side effects, which svoevremennyypriem Tamoxifen is able to prevent. Unlike other means, such as exposure, the substance is neither androgenic nor anabiotic.

Pharmacological effects

Tamoxifen is a non-steroidal anti-estrogen agent that has weak estrogenic properties. Its action is based on its ability to block estrogen receptors. Tamoxifen, as well as some of its metabolites with estradiol, compete for sites with cytoplasmic estrogen receptors in tissues of the breast, uterus, vagina, pituitary and tumors with levels elevated estrogen receptors. In contrast, the estrogen receptor-tamoxifen receptor complex will not stimulate DNA synthesis in the cell nucleus and will inhibit cell division which leads to regression.

Side effects

Dyspepsia, nausea, edema, leucopenia, thrombocytopenia, hypercalcemia, keratopathy, retinopathy, dysmenorrhea, tides, metrorrhagia, vulvar itching, reversible cystic swelling of the ovaries.



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